Sentence examples for penetration issues from inspiring English sources

The IA model of drug delivery can target agents directly to the site of injury while blunting systemic effects, dose penetration issues, and administration delay that have plagued the intraperitoneal and oral drug administration models.

It also can lead to arc stability and penetration issues, and increased spatter, due to its much more energetic arc plasma.

One aspect concerns the preclinical stage of the drug development where insufficient dose-response or time-window studies, inappropriate drug delivery protocol, or brain penetration issues are often encountered.

Thus, as an alternative, telomerase inhibition was assessed in a subcutaneous model to circumvent BBB penetration issues and permit longer treatment duration in this aggressive tumor model.

Much effort has been made to use a longer NIR wavelength and wavefront shaping technique with the control of multiple light scattering to overcome tissue penetration issue [55, 56].

Exciting sunitinib by near-infrared light through a two-photon strategy may solve the tissue penetration issue.

The limited and regionalized effects of lovastatin at tolerable concentration might reflect a lovastatin penetration issue, as this has been reported with other compounds [ 24] and is known as a limitation of the model.

Meanwhile, aiming to high penetration level, many issues emerge regarding their behavior under grid disturbances.

Despite its promising success, PV penetration presents various issues and its impact on the distribution system has to address for seamless integration in the power system.

With the rapid increase in the rate of distributed generation (DG) penetration depth, the issues of improving micro-grid transient become more significant.

This reflects, at least in my mind, that KI does not want a thorough penetration of this issue again".