Sentence examples for penetration administration from inspiring English sources

It is insufficiently absorbed from the GI tract and due to its poor ocular penetration, administration of higher doses via the intravenous route is needed [ 4].

However, because this drug can lead to reduced MRI contrast enhancement, delayed capsule formation, increased risk of intraventricular rupture and decreased antibiotic penetration, administration was discontinued as soon as the patient was stabilized.

The IA model of drug delivery can target agents directly to the site of injury while blunting systemic effects, dose penetration issues, and administration delay that have plagued the intraperitoneal and oral drug administration models.

The purpose of this study was to design microspheres combining sustained delivery and enhanced intracellular penetration for ocular administration of antisense oligonucleotides.

While adopting transdermal drug delivery administration route, drug penetration is the point of prime concern.

It is likely due to lack of potency, late administration, and poor penetration into the brain cells [ 7, 32].

This compound was observed to possess good blood brain barrier penetration based on an intraperitoneal administration study on mice.

Together, these data demonstrate that Fc-like peptide mimetics of antibody function can be generated opening new options for production, mode of administration, and tissue penetration.

This method of delivery might possibly circumvent the challenges that possibly exist with intravenous administration where tissue penetration is concerned, although this remains to be demonstrated objectively.

Both optical imaging studies on Cy5.5Angiopep-2 in live animals and direct biochemical analyses of ANG1005 concentrations subsequent to intravenous administration indicated fast penetration into general brain tissue.

Penetration of dextran by co-administration of iRGD peptide was also observed in TGs, the areas of dextran distribution were extended 1.7-fold in PC-03 (P=0.008), 3.0-fold in PC-09 (P=0.001), and 1.9-fold in PC-10 (P=0.040).