A simple scoring system intended for clinical use was constructed and internally validated, pending validation in an independent cohort.
Conclusion:SCDAs and glutamine/valine may be valuable markers of cardiovascular risk among persons living with HIV in the future, pending validation in larger cohorts.
Serum SPD is a promising lung-specific biomarker to track clinical health outcomes of patients with COPD, pending validation of these early findings with larger clinical studies.
Preliminary analysis of the data also suggests the possibilities of ethnic group specific disease related polymorphisms, pending validation in future studies.
4) Characterization of enzymes that could be linked to posttranslational modification of teretoxins, pending validation by proteomic analyses of terebrid venom duct components.
To validate treatments tested in clinical trials, and to make the results of different studies comparable, it seems relevant to use a full geriatric assessment such as CGA, allowing fit patients to be separated from the vulnerable and fragile, pending prospective validation of geriatric screening tools (Luciani et al, 2010; Pal et al, 2010; Soubeyrand et al, 2011).
Its broad mandate has been successfully achieved, only pending the validation of its accelerator with its conventional facilities.
Consequently, pending experimental validation by gel-shift assays or other methodologies TargetRNA data need to be treated as truly putative.
Thus, pending further validation, our results present preliminary data supporting the hypothesis that microRNA signatures may be used to complement mRNA gene expression signatures of chemosensitivity.
Apart from bevacizumab, potential therapeutic targets such as estrogen receptor [ 5], hedgehog signaling [ 6] and mTOR inhibitors [ 7] are pending clinical validation.
As such, we elected to retain this criterion in the GET-D, pending additional validation studies.
