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In such cases, gaps before and after the query sequence simply represent regions where sequence data were not collected rather than true evolutionary events, so these gaps are not penalized within the scoring matrix.
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It would also bar permits if the company had been penalized with fines of $10 million or more under the Clean Air or Clean Water Acts within a seven-year period.
These rates increased to 26.4% and 21% after forbidding matings that exhibited more than four faults, even in herds 2. Final forbidding rates amounted to 37.1% and 37.5% after excluding in herds 2, the matings being more penalized than the average within-cow penalty.
Within our penalized (RE ML framework, this can be achieved by substituting the structured matrix for the scale matrix Ω in (Eq. 10).
Gene selections with survival outcome data in the statistical literature are mainly within the penalized Cox or additive risk regression framework [ 3- 8].
Core reactions, including core transporters, are not penalized in order to find, within the different alternatives sets of reactions that allow the production of biomass or required metabolites, the one that contain the highest number of core reactions.
Comparing the different penalized regression models, we can see that in within-cohort prediction, dense models (RR or many input and retained SNPs) tend to outperform sparse models (LASSO and EN or few input SNPs).
For failing to deliver on time and within its budget, Lockheed was penalized about $95 million over the last few years.
Because the benefits of stents for patients having heart attacks are so clear, hospitals equipped to perform the procedure are penalized if a stent is not placed within ninety minutes of the patient's arrival in the emergency room.
You pretty much have to learn to conform to those within certain parameters or you're penalized.
Second, modeled motion within a short time scale is penalized.
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