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For instance, the nanoparticle surface is conjugated with poly ethylene glycol) (PEG) to reduce the mononuclear phagocyte system-mediated clearance.
We have previously shown model polystyrene nanoparticles up to 114 nm in diameter were able to rapidly diffuse in normal brain tissue, but only if coated with an exceptionally dense layer of poly ethylene glycol) (PEG) to reduce adhesive interactions.
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To help keep the guitar in tune longer, let this helical coil top slightly press on the string section (end) that comes out of the opening of this tuning peg rod to reduce string slippage.
Building on earlier work that used PEG-diisocyanate to reduce thrombus formation on Dacron vascular grafts, Deglau et al. delivered N-hydroxysuccinimide-PEG (NHS-PEG) to the arterial surface using the Boston Scientific Remedy balloon.
HPMA copolymers not only fail to induce a significant immune response against them but they have similar capacity as PEG to dramatically reduce the antibody response against proteins bound to them as a targeting moiety or for the therapeutic purpose.
If a peg is sticking, pull the peg slightly out and, using a common graphite pencil, draw on the peg in order to reduce the friction.
Here in this study, surface modifications of PLGA NP with PEG are expected to reduce non-specific interactions with RES systems and prolong the blood circulation time.
In Japan, when patients transition from acute hospitals to non-acute hospitals or nursing homes, they are often required to undergo PEG in order to reduce the burden on staff who help patients with swallowing difficulty to eat.
A novel extracorporeal PEG technique, Direct-PEG, has been developed to reduce the risk of peristomal infection and implantation.
Only 3.3 mol% of PEG 2000 was used in this study as a higher PEG content is known to reduce adsorption of liposomes onto cells [ 41].
Indeed, weak PEG density was shown to reduce the thermodynamic barrier to protein adsorption.
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