Sentence examples for peg coupling from inspiring English sources

However, protein adsorption could not be completely abrogated, even at high PEG coupling concentration.

PEG coatings were even effective at low in-solution PEG concentrations,d and the amount of albumin adsorption decreased as PEG coupling concentrations were increased.

As can be seen in Figures 3(b)– 3 e), the relative intensity of this peak increased with star PEG coupling concentration, hence highly suggesting that the density and/or thickness of PEG coating increased with PEG concentration.

EL was measured in both genotypes under 6% PEG coupled with simultaneous cooling treatment in both gradient cooling (hereafter referred to as 'GC', Figure  2a) and non−acclimated freezing (hereafter referred to as 'NAF', Figure  2b) modes.

Direct ELISAs similar to those shown in Figure 3 were performed on sera from groups of three rabbits immunized with mPEG or HO-PEG conjugates of porcine uricase in which an average of 2.3 molecules of 10 kDa PEG were coupled per uricase subunit (see Figure S6).

Briefly, PEG-PCL diblock copolymers were prepared by ring opening polymerization of ε-CL initiated by MPEG using stannous octoate as catalyst; PEG-PCL-PEG triblock copolymers were synthesized by coupling PEG-PCL diblock copolymers using HMDI as coupling agent [ 18, 24].

The plasma clearance of PEG-alpha 2-macroglobulin-trypsin was prolonged significantly compared to native alpha 2-macroglobulin-trypsin, particularly when a high-molecular-weight PEG was coupled to the protease inhibitor complex.

Studies have shown that PEG liposomes coupled to transferrin are able to achieve preferential receptor-mediated targeting of C6 glioma in vitro [ 110, 111].

A readily available amine/azide bifunctional PEG was coupled to the benzoic acid by activation with HATU in the presence of TEA in anhydrous DMF to give compound 7 in 93% yield.

The unusually high degree of selectivity for mPEG of the anti-PEG antibodies detected in sera from two of three rabbits immunized with mPEG-uricase suggests that the immunogenicity of this porcine enzyme to which the PEG is coupled may influence the impact of the terminal methoxy groups on the specificity of the antigen-binding sites of the anti-PEG antibodies (see Figure 1).

This work aims to evaluate the effects of two different surface modification strategies: PEG conventional coupling (PEG-Lpx) and postpegylation technique (postPEG-Lpx), on lipoplexes obtained between liposomes and siRNAs.