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Estimates of heritability from non-pedigreed populations also rely heavily on getting good estimates of pedigree relationship [ 3], which is difficult unless relationships are very close, and environmental confounding can still a source of bias.
The Pedigree RElationship Statistical Test (PREST) was used to verify the pedigree structure and detect relationship misspecification.
Using a genomic relationship matrix increased the accuracy of breeding values relative to using a pedigree relationship matrix.
In classical quantitative genetics, the correlation between the phenotypes of individuals with unknown genotypes and a known pedigree relationship is expressed in terms of probabilities of IBD states.
Based on information collected through the Family History Form, we established family and pedigree relationship of every subject.
The Pedigree RElationship Statistical Test (PREST) program [34] was used to estimate degree of relatedness between individuals in our families by estimating the probabilities P0, P1, and P2 of two individuals sharing 0, 1, and 2 alleles identical-by-descent over the 515 microsatellite markers successfully genotyped in the primary genome scan families.
The pedigree relationship between this sire and daughter is 0.954 (Mike MacNeil, personal communication).
Estimated breeding values were obtained using the pedigree relationship (PBLUP) or the genomic one (GBLUP).
The same pedigree as defined above in the paragraph on data was used to derive the pedigree relationship matrix.
However, the C genome revealed more complex groups, making it difficult to draw clear conclusions about the pedigree relationship.
Animal models using genomic or pedigree relationship matrices and Bayesian model averaging methods were used for training analyses.
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