Sentence examples for pedigree I from inspiring English sources

In such a case the pedigree (i.e., a pictorial representation of family history) is vertical that is, the disease passes from one generation to the next.

Mainstream classical Indian epistemology is dominated by theories about pedigree, i.e., views about knowledge-generating processes, called pramāṇa, "knowledge sources".

For the pedigree i, let n T be the number of informative nuclear families and n S be the number of informative discordant sibships.

Without loss of generality, assume h H is the most frequent haplotype, and for the rest of H − 1 haplotypes, the summary random variable for the pedigree i is defined as: 2 where w k is the weight for the haplotype k.

The linear model was: y = μ 1 + Zu + e where, μ is an unknown mean; 1 is a vector of ones; u = { u i } is a vector of sire effects; u i is the effect of sire i in the pedigree (i = 1, 2,..., 624) and Z is an incidence matrix of order 333 × 624 linking u to the observed data.

For k-th haplotype, the hPDT statistic for pedigree i is thus defined as: 1 Where is the number of transmissions minus the number of non-transmissions on the h th haplotype in trio j, and is the number of copies in the affected sib minus the number of copies in the unaffected sib in sib-pair j.

Enrollment of bilineal pedigrees (i.e., tics in both paternal and maternal sides) is permitted, but discouraged as they are less informative [ 34].

Another is that prior estimates tended to be obtained from selected pedigrees (i.e., selected on the basis of disease status) [ 8], whereas this analysis features a "randomly" (i.e., non-phenotypically) selected pedigree.

Using single- and multiple-QTL mapping analyses on each pedigree and on the combined pedigree, we investigated the benefits of combining pedigrees (i.e. doubling the pedigree size) to refine the location of QTL for growth and fatness on SSC2, 4 and 6.

When the two pedigrees were analysed independently, two different most likely QTL positions were obtained, in accordance with previously published results on the two pedigrees, i.e. at 0 cM in the French pedigree [ 11, 17] and in an interval between positions 20 and 50 cM in the Dutch pedigree [ 22, 23].

The proposed method can also be generalized to IBD tracing in more complex pedigrees, i.e., beyond a single generation, allowing information from various types of relatives to be exploited by linkage analysis e.g., [ 13].