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This pilot work also informed the identification of domains, which were broad categories describing groups of outcomes, supported by a leading source in health measurement [ 30] and corroborated against the domains described by the Patient Reported Outcomes Measurement Information System Pediatric Self- and Proxy-Reported Health Framework [ 13].
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Applying Interactive Mobile health to Asthma Care in Teens (AIM2ACT) is informed by the Pediatric Self-management model, which posits that helpful caregiver support is facilitated by elucidating disease management behaviors and allocating treatment responsibility in the family system, and subsequently engaging in collaborative caregiver-adolescent asthma management.
The PROMIS pediatric self-report items were converted into proxy-report items before undergoing cognitive interviews.
The PROMIS pediatric self-report instruments are limited to ages 8-17.
Proxy-report items were selected only from the PROMIS pediatric self-report items.
Pediatric self-report should be considered the standard for measuring patient reported outcomes (PRO) among children.
All of the pediatric self-report items were converted into proxy-report items and new items were not created.
Children completed the pediatric self-report version of the survey and parents or guardians completed the proxy-report version of the survey.
The proxy-report items were developed from the existing PROMIS pediatric self-report content domains [ 3- 7, 9] and aimed to include proxy respondents with children ages 5-17 years of age.
Compared with existing pediatric self-report measures, PROMIS offers more specific measurement of general health domains, but also the flexibility of using various short forms or computerized adaptive testing that all report on the same metric.
For FDA-endorsed clinical trials that would use the PEESS™ v2.0, it may be that presently we are only able to obtain specific PRO based labeling for pediatric self-report ages 8-18 years of age.
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