The distance between the intercepts is the peak width.
The minimum peak width that can be resolved with this system is 50 pm.
Peak width calculations situated particle sizes in the nanometric range.
Average chromatographic and mass spectrometric peak width resolutions were set to 0.3 min and 30,000 FWHM, respectively.
For this reason, peak width is of major concern in chromatography.
For precursors peak picking the following parameters were used: correlation threshold – 0.7, minimum signal to noise ratio – 5, minimum peak m/z – 50, maximum peak m/z – 100,000, minimum peak width – 0.02 Da, expected peak width – 0.2 Da, maximum peak width – 2 Da.
The analysis cycle time was 4 min and the peak width was 0.8 min.
Moreover, structural parameters are optimized considering both transmission rate and spectral peak width.
Prediction errors for peak width and resolution were, in most cases, lower than 5%.
The critical resolution, analysis time, and peak width were responses modeled by multivariate linear regression.
Separation metrics examined included peak width, tailing factor, asymmetry factor and resolution of separated protein peaks.
