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Phosphodiesterase type 5 inhibitors (PDE5-Is) improve storage symptoms in benign prostatic hyperplasia patients, despite a lack of effect on peak urinary flow rate.
In population-based studies, the prevalence of moderate-to-severe lower urinary tract symptoms and depressed peak urinary flow rates increases across successively older age groups.
Unlike clinic-based studies in which correlations are almost nonexistent, the population-based studies demonstrate a modest correlation among lower urinary tract symptoms, peak urinary flow rates, and prostatic volume.
Uroflowmetry was performed to measure peak urinary flow rate (Qmax) for all patients.
Secondary endpoints included IPSS responders (≥25%, ≥2-point, and ≥3-point improvement), peak urinary flow rate, peak urinary flow rate responders (≥30% and ≥3 mL/s improvement), total prostate volume, and prostate transition zone volume.
* AUASI, American Urological Association Symptom Index; QMAX, peak urinary flow rate; PSA, Prostate-Specific Antigen; VOL, prostate volume.
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VPI cine loops were derived from these urinary flow phantoms.
urinary flow rate.
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