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The huge number of gathered wavelengths (profiles) is then analyzed and pre-processed using a new proposed simple algorithm named Spectra peak selection (SPS) to select the important wavelengths, then we employ wavelet analysis (WA) to enhance the performance of detection by suppressing noise and redundant information.
The third section exposes our proposed methodology, at the first time we start with the proposed algorithm named spectra peak selection (SPS) then we employ wavelet analysis to improve the quality of selected wavelengths (profiles) by de-correlating and suppressing noise from Optical spectra.
To attain high disease diagnostic accuracy, many studies focus on identifying biomarkers from mass spectral profiles, which are generally a small set of protein expression peaks at selected m/z (mass/charge) ratios, through different machine learning approaches (e.g., peak selection), [ 7, 8].
Peak selection in an optimal way is a challenging problem that will be the subject of future work.
The computer assisted method helps in the chromatographic peak selection and the metabolite structure assignment, enabling automatic data comparison for qualitative applications (kinetic analysis, cross species comparison).
Lowe et al. propose SIFT descriptor which consists of four major steps such as scale-space peak selection, keypoint localization, orientation assignment, and keypoint descriptor [30].
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In contrast, using our statistical peak selections significantly lowers the distance estimation error.
A simple programme was originally developed for the rapid identification and classification of herbal constituents on the basis of the establishment of herbal constituent databases, recognition of the reference compound peaks, selection of the diagnostic ions or fragmentation pathways, classification of chemical groups and formation of group networks.
Peaks selection was done using thresholds based on the posterior probability generated by the software, PP≥0.5, subsequently only the peaks overlapping in replicated experiment were considered.
Figure 7 Localization using our statistical peak-selection method.
To achieve this goal, we propose statistical peak-selection algorithms that significantly increase the localization accuracy.
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