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For this we aligned the peak firing frequency of each unit to 180° (see normalisation in Materials and methods).
Although not directly related to this study, and in mice, Marowsky et al. (2005) identified the subpopulations of interneurons and showed that the firing properties of local interneurons, which are scattered throughout the BLA, had a peak firing frequency within the gamma range.
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In contrast, lateral and medial paracapsular cells, which are located between the lateral BLA border and external capsule and between the medial BLA border and central nucleus, respectively, had peak firing frequencies in the beta frequency range.
Fire frequency increased with human population density from a depopulated period (the late 1600s and early 1700s) to a peak in fire frequency circa 1880.
Furthermore, following this more intense mGluR or AchR activation, recurrent episodes of firing were of a higher mean frequency (peak firing rate: 39.8.7±3.8 Hz; p<0.01; n = 12) and more commonly involved HT bursting (79%, n = 15 of 19) (Fig. 1D).
Most commonly, firing frequency increased within the peak; the effects on the frequency between peaks as well as peak timing were relatively small.
DOI: http://dx.doi.org/10.7554/eLife.02798.018 > -wrap-foot> In response to the contrast-modulated noise stimuli, the peak firing of a cell occurs at the frequency of contrast modulation (F1, at 0.1 Hz).
Conversely, the firing frequency histograms displayed only one peak when the slices were excited using ACSF2 (Fig. 2B).
Color scale indicates frequency with red corresponding to peak firing rate and blue to null firing.
The offset of the input output function was defined as the peak amplitude of the current waveform necessary to reach larger firing frequency than the half of the input frequency.
For comparing electrophysiological properties of different types of Golgi cells, grand average AP waveforms were generated for each cell by averaging peak-aligned APs obtained during 1-s voltage sweeps while adjusting the firing frequency to ∼25 Hz with current injection as necessary, and then by averaging these peak-aligned mean waveforms across experiments.
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