AdCre and pFlox treated cells expressed hVEGF-A165 efficiently reaching the peak expression at 24 h after the transduction.
In particular, 80% of cyclically expressed flagella genes (167 of 207) had peak expression at ZT 21, suggesting that biological functions can be phase specific.
Two of three JMJ-related factors are co-expressed at 6 hr while a third one shows peak expression at 12 hr.
The KAS I and KAS III genes showed peak expression at 28 DAF, whereas the KAS II gene was maximally expressed at 42 DAF.
Clusters 3 and 4, in which genes showed peak expression at P10, were enriched in genes related to metabolism of macromolecules, nucleobase-containing compounds, and aromatic and heterocyclic compounds.
These transporters differ from those in cluster 1 in that they show peak expression at 1 h in phagocytosed cells and decrease in expression by 4 h (Fig. 2c).
Scaffolds with polyplexes embedded within the fibrils of the biopolymer showed peak expression at 7 9 days and showed linear expression for 21 29 days, depending on the polymer:DNA ratio.
Both BNP and NPRA showed a peak expression at day2 after BmK I injection.
Many of the cycling genes show coordinated regulation with peak expression at the same cycling phase (Figure 2B and 2C, 12 h or dusk).
Figure 3 depicts the OMICs Viewer gene expression views (cellular overview) of the four gene sets (the four sub-clusters) that show first peak expression at 0 h, 8 h, 12 h and 20 h respectively.
As expected, the transcription of iNOS and Arg II, but not of Arg I, and the production of IL-6 were observed in M1-polarized MØB6, with a peak expression at 10 hours (Fig. 2).
