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Aerobic energy release during peak exercise is reduced by excessive fat mass, which imposes an unfavorable burden on cardiac function and on oxygen uptake by working muscles [5].
Maximum oxygen uptake capacity (VO2max), the maximal amount of oxygen per unit of time that can be delivered to the peripheral organs including the skeletal muscle (where it is used to sustain muscular contraction at peak exercise), is a bench mark measure of physical performance/work capacity [50].
Cardiopulmonary limitation at peak exercise is well documented in patients with COPD [ 3– 5] and in individuals with overweight [ 6– 10].
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Results: Mean differences ± standard deviation between transcutaneous and arterial tension at peak exercise were 0.4 ± 7.0mmHg and 2.1 ± 3.3mmHg for PaO2 and PaCO2, respectively.
Finally, leg potassium release during peak exercise was found to be similar in all the conditions (result not shown).
The levels of arm venous lactate (Table 1), as well as the levels of arterial and femoral venous lactate (Table 3) and potassium (result not shown) measured during peak exercise were similar in all the experimental conditions.
Due to the small number of participants in our study (n = 7), for each parameter, all the data that were obtained at a given power output (i.e. at 100 W or at peak exercise) were pooled before data distribution was examined (n = 28).
Systemic oxygen extraction after peak exercise was measured.
The mean saturation of oxygen at peak exercise was 87.7% (± 5.7%) and the mean Borg scale for dyspnea at peak exercise was 4.84 (± 2.3).
Measurements at the LT and at peak exercise are shown in Table 2.
Ventilation and tidal volume at peak exercise were ∼20% lower in patients compared with control subjects.
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