Sentence examples for peak effect observed from inspiring English sources

The onset and duration of the responses following the initial unilateral injection were 10 s and 70 min, respectively, with a peak effect observed at 3 min (Fig. 4A).

The combination of less within-patient variation in PG [ 25], longer duration of action and a reduced peak effect observed with detemir relative to NPH [ 26] probably signify that FPG targets are achieved more easily without additional risk of hypoglycaemia.

In RAoSMC, ERK 1/2 phosphorylation was transiently and significantly increased in the presence of CNP (1 µM), with a peak effect observed at 10 min after treatment; this effect was blocked in the presence of M372049 (10 µM; Figure 5).

Higher doses of the SINE compounds (150 nM) resulted in a subtle and gradual increase in nuclear reporter localization, with peak effects observed 8 h or more after drug addition.

In the cervix, CGRP concentrations decreased, but in the L6-S1 DRG and the spinal cord segments, CGRP levels increased, with peak effects observed at day 20 of gestation.

(G ) Acute (30-min) and (H ) chronic (2-week) application of clenbuterol to myobundles (shown in different donors) results in a dose-dependent increase in contractile force with peak effects observed at 1 µM (acute) and 0.1 µM (chronic) and significant reduction in force generation observed at 100 µM (acute, n = 3 myobundles; chronic, n = 4 myobundles).

This was time dependent with peak mRNA effect observed at 12 h after hypoxic exposure (Fig. 6 C ).

Nevertheless, from the peak toxic effect observed 24 h after washout, the percent of pyknotic cells was gradually reduced in all three regions over the next 48 72 h.

The main results of the present study are as follow: (i) 100 000 IU of oral CCF once each month is an efficient strategy to adequately supplement 90% of 25-D deficient and insufficient HD patients; (ii) a plateau of serum 25-D level is observed after 11 weeks (+280%); (iii) no peak effect is observed after 48 h; (iv) no adverse events were observed.

The onset (after initial unilateral injection) and duration of the responses to DADLE were 15 and 300 s, while the peak effect was observed at 140 s.

No peak effect was observed 48 h after the first dose of CCF.