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When exposed to 2,4,6-trinitrotoluene (TNT), the biosensor showed significant absorption peak changes in visible spectra with a concentration-dependent behavior.
The peak changes in diastolic blood pressure by electrical stimulation or exogenous α-CGRP were expressed as percent change from baseline, as previously reported [16, 18 21].
The peak changes in the baseline values of heart rate and diastolic blood pressure elicited by the administration of isometheptene (racemate and enantiomers) were determined.
Two of these genes, cytokine receptor-like factor-1 (Crlf1) and matrix metalloproteinase 23 (Mmp23), showed peak changes in gene expression of 15- and 40-fold on days 4 and 7, respectively.
To understand the role of dislocations in the twin boundary hydrogen interaction peak, changes in the relaxation behavior with thermal cycling were systematically studied by dynamical mechanical analysis for both H-containing and dehydrogenated Ti50Ni50 samples.
However in 6/20, peak changes in P-R were elicited from sites rostral to those eliciting peak changes in P-P (see example in Fig. 3B) and in only 1 was the reverse found.
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Increased expression of ARG1, CCL2, RETLNA, IL-1b, and PTGS2 genes was observed in bronchoalveolar lavage (BAL) cells with peak change in all genes at 24 h.
The frequency of depolarization -induced Ca2+ sparks was markedly increased (1.5 fold, ) in the presence of SNAP, whereas neither the probability of observing sparks (94.0% (15 out of 16 experiments) versus 94.46%(17 out of 18 cells)), nor the peak change in fluorescence (1.74±0.04 versus 1.66±0.06) were significantly different.
The primary efficacy endpoint was peak change in forced expiratory volume in 1 second (FEV1).
The peak change in the increased diameter and fiber number differs for each of muscle [ 14].
TIO 18 μg also demonstrated statistically superior efficacy compared with Placebo MDI (P < 0.001) for peak change in FEV1.
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