Sentence examples for peak cell concentration from inspiring English sources

The peak cell concentration in NS0 batch culture was around 3.109 cells/l.

Fed-batch cultures in OptiCHO achieved 40%% or less of the peak cell concentration observed in fed-batch cultures with ActiCHO P as a base medium.

The composition of basal media and feeds had a substantial effect on peak cell concentrations and antibody titers as shown in Fig.  2a, b.

Depending on the fed-batch strategy, fourfold higher peak cell concentrations and eightfold increased IgG titers (up to 5.8 g/L) were achieved.

This threshold was passed on day 7 in OptiCHO fed-batches and indeed coincided with peak cell concentrations that declined thereafter.

The highest cell and product concentrations of 2.39 × 10 cells/mL and 5.5 g/L were achieved in cultures grown in ActiCHO P supplemented with Feed A and B. Feeding these cultures additionally with FunctionMAX altered the process only marginally reaching peak cell concentrations of 2.13 × 10 cells/mL and IgG titers of 5.8 g/L.

In general, nutrient supplementation of the basal media had a positive effect on cell growth and titers, although a well-balanced basal medium was fundamental, even for the best performing feed supplements, to reach peak cell concentrations around day 7 and maintain antibody secretion until the end of the cell culture (Fig.  2).

Compared with the batch cultures, the peak cell concentrations increased by 280 and 230 %, titers by 670 and 330 %, and volumetric productivities (STY) by 260 and 200 %, and finally, the cell culture process was extended by 11 or 8 days in ActiCHO P and OptiCHO media, respectively.

Compared to earlier processes, these developments allow 10-fold higher peak cell concentrations to be reached and product titers of up to 5 g/L are routinely achieved within 2 weeks of process duration (Jayapal et al. 2007; Yu et al. 2011).

The induced parasites propagated normally and attained peak cell density at an in vitro concentration of berenil, 5.5-fold higher than the IC100 of the wild-type.

In this paper, a linear relationship was obtained between the SWV peak current and the cell concentration in the range 2 × 102 2 × 108 cell mL−1 with a detection limit of 2 × 102 cell mL−1.