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Partial discharge (PD) analysis has been widely used to detect premature degradation of power cables.
Although there are recognized techniques for PD analysis, there is still lack of knowledge about measuring and modeling this phenomenon.
AM conducted cellular proliferation assays and PD analysis.
Within-subject variability in PK parameters was disregarded in the PD analysis.
Population pharmacokinetics (PK) modeling, individual PK simulations, and PK-pharmacodynamics (PD) analysis identified a threshold HCQ peak concentration that predicts therapy-associated AV accumulation.
Instead, we found that two-thirds of articles contained negative outcomes, and a similar proportion described PD analysis as affirming hypotheses in discussion.
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To date, methodologies available for PK-PD analysis barely suppose the use of powerful computing resources.
Fourteen patients were evaluable for this PK-PD analysis.
Of these, TL-PD analysis by itself accounted for 180 (53%) patients, and NTL-PD analysis itself accounted for 287 (84%).
Patients who discontinued MMF because of intolerance or non-compliance or both were excluded from the final PK-PD analysis.
One patient had MMF side effects (diarrhea, nausea, and abdominal pain) requiring its discontinuation and thus was excluded from the PK-PD analysis.
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