Exact(2)
A family of proteins located at the centrosome that react with human autoantibodies include pericentrin, ninein, enolase, PCM 1 and a newer autoantigen, Mob1 [ 10, 11].
When the sera were tested for IgG antibodies by immunoblotting, 10/12 reacted with at least one of the five centrosome proteins: ninein, PCM 1, γγ-enolase, Mob-1, or pericentrin (Table 1).
Similar(6)
Generally peptide descriptor sets obtained from the field of Quantitative Sequence-Activity Modeling (QSAM) are used in PCM [1, 11 15].
Total plasma cells in MGUS were more likely to express CD19 (13/29 cases, 45%) than those in PCM (1/32 cases, 3.1%, p < 0.001).
C. Filter through 0.45 µm syringe filter with a 10 ml syringe and dilute filtered PCM 1 1 in fresh phenol red free medium.
Published online: May 3, 2007 The centrosome is the main microtubule-organizing center in animal cells, and it consists of a pair of centrioles surrounded by an amorphous pericentriolar matrix (PCM) [1].
The cells were further stained for immunofluorescence of the centrosome proteins PCM-1 and pericentrin.
Moreover, the centrosome protein PCM-1 was absent from these foci (Fig. 5A).
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