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It has been demonstrated repeatedly that ADC values inversely correlate to PCa grade [18].
DCE improves the detection of PCa and DCE parameters correlate with PCa grade [69, 70, 71].
The results revealed that the overall PCA grade in both samples was approximately 70% with around 3.4% dust generation.
However, our results did not change substantially when MetS risk was stratified according to PCa grade.
The PCa grade captured at the time of diagnosis depends on screening practices and does not take into account the whole history of PCa progression.
Odds ratio and 95% confidence interval were determined by logistic regression for the associations between IL-10 genotypes and haplotypes with the risk of PCa and advanced PCa grade.
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Despite revisions in 2005 and 2014, the Gleason prostate cancer (PCa) grading system still has major deficiencies.
Contrast-enhanced targeted US allows for detection of significantly higher Gleason score, which is important for PCa grading.
Approximately 44% of the patients had low-grade cancer (Gleason score <7), 40% had intermediate-grade PCa (Gleason score =7), and 16% had higher-grade cancer (Gleason score >7).
Data from patient tissues has suggested that the relative expression of KLK2 is increased in malignant tissue compared to benign and healthy prostatic tissue, and the intensity of hK2 immunostainings in, e.g., lymph node metastasis correlates better with PCa tumor grade than that of PSA [13, 14].
Prostate tissue array having normal prostate tissues and multiple PCa (Gleason grade 6 10) tissue spots were obtained from Biomax (Bethesda, MD, USA).
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