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However, these gene sets are also enriched in cancers with Gleason score 8 and 9, thus making them too ambiguous for early stage PCa assessment (Additional file 1: Figure S4).
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If the patient wishes to have a genetic PCa risk assessment, two blood samples will be taken: one for the PSA test and one for the genetic PCa risk assessment (SNP test).
The European Randomized Study of Screening for Prostate Cancer (ERSPC) risk calculators (RCs) are validated tools for prostate cancer (PCa) risk assessment and include prostate volume (PV) data from transrectal ultrasound (TRUS).
Gleason scoring represents the standard for diagnosis of prostate cancer (PCa) and assessment of prognosis following radical prostatectomy (RP), but it does not account for patterns in neighboring normal-appearing benign fields that may be predictive of disease recurrence.
They recruited 34 patients for a genetic PCa risk assessment.
To explore sociocultural aspects of genetic PCa risk assessment in patients at high PCa risk.
Several biomarkers, which could be novel tools to improve PCa risk assessment, showed promising prognostic value.
11 13 14 This genetic PCa risk assessment tool needs further investigation in a clinical setting.
Valid instruments for individual PCa risk assessment have been called for.
Use of genetic PCa risk assessment may reduce the number of low-risk individuals who get screened unsystematically.
Five of the patients wished to have a genetic PCa risk assessment and provided a blood sample.
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