Sentence examples for pause distribution from inspiring English sources

To estimate the first pause distribution, we used the model described by Niedermayer et al. (2012) with ω = 2 × 10.

With the exception of the pause duration distribution at 2 pN, for which the amount of data is limited (N = 6), all the distributions are well fitted by a single exponential function.

Thus, the pause frequency distribution perfectly matched the ground truths, but this pattern might not have external validity.

(b ) Mean duration of the ATPγS-induced pauses extracted from fitting the pause duration distribution to an exponential.

(f ) Mean lifetime of ATPγS-induced pauses calculated from single-exponential fits to the pause duration distribution at 3 mM [ATP] and 1 mM [ATPγS].

The blue dashed line represents the simulated pause duration distribution for the mutant enzyme, using a k f1 value of 4 s−1.

The green dashed line is the simulated pause duration distribution for nucleosomal DNA transcription by the mutant enzyme, using a k f1 value of 4 s−1.

The resulting pause duration distribution is given by: where I1 is the modified Bessel function of the first kind, and kf and kb are the forward and backward stepping rates during backtracking.

Furthermore, the single-exponential dependence of the pause duration distribution indicates that the exit from the paused state is governed by a single rate-limiting event presumably the exchange of an ATPγS molecule with one ATP which is present in saturating concentrations, as proposed for other ring ATPases (Chistol et al., 2012; Sen et al., 2013).

(A ) Violin plot of the Pol II pausing index distribution shows that pre-MBT genes (during pre-MBT stages) display less Pol II pausing than MBT genes (during the MBT stage).

In the presence of the nucleosome, Pol II pauses, and the distribution of pause durations was similar to that on bare DNA, except that it shifted toward longer pauses.