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DNA fibre analysis of replication at fragile sites revealed paucity of active replication origins in these regions [20].
These highly consistent results indicate that in C2C12 myoblasts, chromatin at the nuclear periphery is largely characterized by the paucity of active histone modifications.
Our experimental results and bioinformatic analyses in mouse C2C12 myoblasts suggest that chromatin at the nuclear periphery is characterized by the paucity of active histone modifications rather than the enrichment of repressive histone modifications.
These findings further support the notion that chromatin at the nuclear periphery is characterized by the paucity of active histone modifications, which may have implications on how peripheral gene positioning affects transcription regulation in mammalian cells.
Giardia lamblia (intestinalis) and Cryptosporidium parvum are the two most important intestinal parasites infecting North Americans but there is a paucity of active population-based surveillance data from Canada.
Monocytes and granulocytes have an overall reduced transcriptional activity of a large number of genes compared to their precursors [ 16], in our study reflected by the relative paucity of active RNA Pol II signals and tiny nucleoli.
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Single cell imaging and genomic analyses have provided consistent evidence on the paucity of several active histone modifications at the nuclear periphery both at the microscopic and the molecular levels in C2C12 myoblasts.
This suggests that there is an extreme paucity of data on the active transcription of the genes of cryptic WO prophages.
A second difficulty has been a paucity of realistic trials that use active placebos or compare drugs believed to be disorder specific (according to current diagnostic classifications or theories) with other drugs known to exert some psychoactive effects.
Despite the abundance of active smokers, there is a paucity of data describing nicotine withdrawal, and its prevention and treatment options in the critically ill.
A beta error probability of 0.10 (lower than the commonly used 0.20) was chosen because of the paucity of new drugs that may be active in melanoma.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com