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To assess potential influences of selective constraints on dTRX, we also included average random mutational impacts estimated from the real patterns of mutation in the yeast genomes as well.
A study of 25 breast cancers revealed diverse patterns of mutation, with a variation in the number of mutations and in the identity of mutated genes, such that no commonly point-mutated kinase gene was identified [10].
This study investigated the patterns of mutation to fluconazole resistance in C. neoformans in vitro.
These bi-cliques define "patterns of mutation" which seem to be associated synergistically to longevity.
Strand asymmetry is the consequence of selection and asymmetric patterns of mutation between the two strands [47], [48].
We also found 261 SNPs in the patterns of mutation that are characteristic markers for these haplogroups.
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However, at that time, there had only been limited characterization of patterns of mutations imprinted by mutational processes.
He produced mutant flies and recorded the patterns of mutations in generation after generation of offspring.
But since the Y chromosome and mitochondrial DNA clock up occasional changes or mutations every thousand years or so, on much the same time scale as human population splits, different ethnic groups tend to have characteristic patterns of mutations.
The aim of this study was to identify patterns of mutations in early stage node negative lung adenocarcinoma.
The patterns of mutations in both oral and esophageal cancers are extremely heterogeneous, in agreement with epidemiological data showing that multiple factors may act in conjunction in the pathogenesis of these cancers (including in particular tobacco and alcohol).
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