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RNA expression documents patterns of human transcriptome variation across individuals and tissues.
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Recently, the de novo assembly of human transcriptome has been reported using ABySS program.
Tissue-specific 1α,25- OH 2 1α,25- OH 2esponses may involve complex non-genomic/genomic cross-talk anD3modulation of downstream sigrowthby distinct lineage-specific expresponsesatterns of the humay transcrinvolve
Unspliced EST data, although typically disregarded in transcriptome analysis, can provide interesting insights into the structure of human transcriptomes.
The assessment of gene expression of the human transcriptome using microarray technology is a powerful tool for identifying genes and gene expression patterns involved in mechanisms of normal organ function and the pathogenesis of disease [ 1- 3].
The current findings illustrate part of the hidden complexity of the human transcriptome.
Hypoxia results in a change in expression of a significant portion of the human transcriptome.
Our understanding of the complexity and diversity of the human transcriptome is far from being comprehensive.
The representation of the human transcriptome is reduced taking advantage of correlation in gene expression.
The emergence of isoform-sensitive microarrays has helped fuel in-depth studies of the human transcriptome.
This array contains 6.5 million probes targeting known and predicted exons of the human transcriptome [ 27].
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