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We first determined the expression patterns of FEAT in lung cancer, breast cancer, and hepatocellular cancer tissues.
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Therefore, we insisted that individuals' understanding about the importance of FEAT to their industry type would strengthen the relationship between SEP and ATD toward the FEAT.
Furthermore, in this study, we experimentally investigated the direct regulation of FEAT by miR-16 and the biological role of miR-16 targeting FEAT in human cancer cells.
Using these approaches, miR-16 was identified as a candidate regulatory miRNA of FEAT.
However, despite these recent advances in our understanding of the important roles of FEAT in cancer progression, the precise molecular mechanism through which FEAT is upregulated during tumorigenesis remains largely unknown.
Finally, we demonstrated that the repression of FEAT by miR-16 promoted the apoptosis of cancer cells.
After measuring the protein levels of FEAT in these cancer tissues and the corresponding noncancerous tissues, we found that FEAT protein is dramatically overexpressed in cancer tissues but totally absent in normal tissues (Fig. 1a).
We then experimentally validated miR-16 as a direct regulator of FEAT using cell transfection and luciferase assays.
Drawing on Argentina's rich literary heritage — the forking paths of Borges, the hopscotch patterns of Julio Cortázar — Mr. Llinás pulls off the rarest of cinematic feats.
Kings Of Tomorrow feat.
Pick out your feat(s) A list of feats and their descriptions can be found in the PHB.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com