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Treatment failure may be explained by different patterns of drug uptake distribution.
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The in vitro drug release pattern of the drug showing an initial fast release within the first 6 h followed by an eventual gradual release over 72 h could well be exploited for therapy regimes spread out over long durations thereby reducing the frequency of drug uptake.
Registry data offer valuable insights into patterns of drug use and can provide a means of tracking uptake of guideline recommendations.
Multiple different patterns of drug resistance were found.
Pharmacokinetics: temporal pattern of drug concentration within a patient's body, due to dosing patterns and physiological processes such as uptake and breakdown of the drug.
Intraarterial (i.a). chemotherapy offers the potential benefit of increasing tumor drug delivery because of first-pass drug uptake, while minimizing systemic drug levels and toxicity.
Figure 3 Measurement of cellular fluorescence and drug uptake.
Six studies assessed the influence of time on new drug uptake by encompassing many potential influencers for example, overall acceptance, growth in patient base, and the aggregate diffusion pattern in a geographic area.
This optical effect may be employed to improve the drug uptake properties of Fe3O4 nanoparticles.
Two distinct patterns of TNF uptake were observed.
Several studies have described patterns of FDG uptake specific for peritoneal metastases including diffuse uptake spreading uniformly throughout the abdomen and focal peritoneal uptake representing deposits.
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