These times were chosen because at 6 hours cells are beginning to establish a pattern of differentiating cells, at 12 hours proheterocysts are committed to becoming heterocysts [ 46], and at 21 hours nitrogen-fixing heterocysts are fully differentiated.
On the basis of our results, we are less confident of the use of the proposed CK7/20 patterns for differentiating short-segment BE from gastric intestinal metaplasia.
The clear discrimination between the two expression patterns suggests a gradual order of differentiating cells, whereas miRNAs function as enhancers of robustness in gene regulation [ 34, 35].
The MYB expression pattern is reminiscent of markers of differentiating cell types such as Clara cells and MCCs, which are interspersed in the bronchial epithelium.
The benefit of differentiating between different patterns of non-adherence which are not evident using global indices of adherence have previously been demonstrated by Ajit et al. [ 55].
Contrast enhancement allows better assessment of nodes, vascular structures and branching pattern for differentiating between vessels and nodules.
Pattern classification of dermoscopy images is a challenging task of differentiating between benign melanocytic lesions and melanomas.
A more efficient way of differentiating PsA from RA by MRI is to study the pattern of joint involvement.
Examination of patterns differentiating high, moderate and low (overall) impact intervention research at the verification panel and further thematic analysis of interview transcripts identified six key factors that particularly contributed to these impacts.
Thus, it enables multivariate analyses of methylation patterns in differentiating cell lineages (like those from Bock et al., 2012), but it may not provide much improvement when analyzing essentially independent samples (like distantly related terminally differentiated cell types).
