Sentence examples for patterns of copy from inspiring English sources

Different subtypes of breast cancer had different patterns of copy number and expression for each TDRD.

Integrative analysis identified a pattern of paired intra-chromosomal translocations flanking focal amplifications and asymmetrical patterns of copy number variation flanking breakpoints of translocations.

Patterns of copy number alteration have proven valuable in classification of cancer subtypes and can serve as predictors of patient outcome [19].

Through the application of a classification algorithm, we now provide the genome-wide evidence that distinct patterns of copy number aberrations exist in metastatic melanomas.

Specific patterns of copy number change and genetic instability that correlate with patient outcome, including simplex, sawtooth and firestorm, have been described in breast cancer [31].

For example, genome-wide analysis of breast tumors by numerous techniques have reproducibly demonstrated recurrent patterns of copy number alteration (CNA) [3], [4], [5], [6], [7], [8], [9], [10], [11].

Natural selection shapes genome wide patterns of copy-number polymorphism in Drosophila melanogaster.

Their unique patterns of copy-number changes suggest that the two phenotypic subclasses of BRCA2 tumors develop in different ways.

Similar patterns of copy-number alternations were associated with chromothripsis in several other studies including the original work by Stephens [ 6, 22– 25].

Both studies found purifying selection to be involved in patterns of copy-number variants, but this information cannot be considered to be exhaustive.

In this study, we show that breast tumors from BRCA2 999del5 mutation carriers, displaying luminal- or basal/triple-negative phenotypes (TNPs), differ with respect to patterns of copy-number changes and markers of pRb/p16 pathway dysfunction, suggesting divergent paths of tumor evolution.