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These interaction patterns of compound 32 with the wild type and mutated forms of protein suggested that the modification at R2 position could increase the activity of compound.
In this section we have shown that cyclic sine and cosine curves with periods dividing 24 hours fit well to the diurnal patterns of compound abundance.
From a learning-theoretical point of view the task examined here belongs to those in which the animal has to discriminate patterns of compound stimuli (color, position, sequence) to form conditional discriminations (e.g. serial feature positive or negative tasks, [18]).
The first function, common to all cell lines, learns the shared patterns of compound activity against all cell lines (e.g. substructures enriched for compound activity).
A striking finding from the current study is the lack of similarity in the patterns of compound activity in cells derived from the same tissue but from different species (e.g., human HepG2 and rat H-4-II-E hepatoma cells).
Second, as our method phases coding and non-coding cis-regulatory sequences together, one can study patterns of compound heterozygosity and linkage of human immune variation [ 7, 16, 17].
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The difference between absorption patterns of compounds is related to various defects created in the lattice.
Figure 1a shows the diffraction patterns of compounds of GCs, along with the diffraction pattern of PGs without thermal treatment.
The hydrogen bonding patterns of compounds 1 3 are compared with the hydrogen bonding pattern of compound 4 in Figure 5. Figure 5 The comparison of hydrogen bonding pattern of compounds 1 3 with reference compound 4. Hydrogen bonding of reference compound with Arg38 (a) and Hydrogen bonding of compound 1-3 with Arg38 (b).
Figure 7 Visualizing the relationship between the staining patterns of a reference probe (located at the upper left corner of the array; probe structure indicated by arrow) and the staining patterns of compounds with different chemical structures.
Identify patterns of compound-induced biological response in order to characterize toxicity pathways, facilitate cross-species extrapolation, and model low-dose extrapolation.
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