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"The abstract forms created by oil fields resemble the shapes and patterns of circuit boards," Henner notes.
As a general rule, it is worth noticing that the patterns of circuit activities, which account for cell functionalities, cannot be easily derived from the changes in gene expression.
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Then on command, they all settle with pinpoint accuracy, precisely touching a pattern of circuit wires, each at just the right point of contact.
Former filmmaker and current artist Theo Kamecke sees the intrinsic beauty of the purely functional patterns on circuit boards.
Although the impact of this temporal versatility and cellular specificity has been greater for basic science than clinical research, it is natural to ask whether the dynamic patterns of neural circuit activity discovered to be causal in adaptive or maladaptive behaviors could become targets for treatment of neuropsychiatric diseases.
Rather than looking at where things happen in the brain, as in small regions missing dopamine, the approach focuses on when things happen, as in the dynamic firing patterns of large circuits of neurons.
Global and/or local changes in the excitability and connectivity patterns of cortical circuits underlie most neuropsychiatric conditions and their treatment.
These properties enable reliable high-resolution optical recordings of spatiotemporal activity patterns of neural circuits in the intact brain.
Examples include the three-dimensional structure of proteins [ 6, 7], secondary structure of RNA [ 5, 8- 10] and the gene activity patterns of regulatory circuits [ 4, 11- 14].
Of the 16,072 possible equilibrium expression patterns of three-gene circuits (Methods), circuits with any one identity mapping had a latent repertoire of 2372 (14.8%) phenotypes, whereas circuits with a transition mapping had a latent repertoire of 415 (2.6%) phenotypes.
This trick involves printing the pattern of the circuit on to the ITO using a rubber stamp.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com