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These differential expression patterns of adhesion molecules and cytoskeletal proteins further supported our beliefs that the presence of epithelial- or mesenchymal-like phenotypes adapted by the two types of ovarian tumor cells could contribute to cell-type dependent penetration/invasion strategies.
In the present study we demonstrate that DHEA has distinct in vitro effects on surface expression patterns of adhesion molecules of endothelial and neutrophil origin.
The results were also analyzed considering the patterns of adhesion on HEp-2 cells, demonstrating that aEPEC is able to form biofilm on an abiotic surface independently of this phenotype.
The latter cytokines are able to induce the expression of distinct patterns of adhesion molecules on the luminal surface, thereby promoting a site- and cell-specific recruitment of circulating leukocytes.
By combining different conditions of neutrophil and endothelial activation, we intended to mimic patterns of adhesion molecule expression as they have been observed during local inflammation and different stages of sepsis-associated systemic hyper- or hypo-inflammation [ 1, 2, 8- 10, 29- 31].
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The two samples differed in their pattern of adhesion and invasion.
Outside the pore (on the rest of cell surface), a derivatized or a non-derivatized cantilever has the same pattern of adhesion force.
Migration displayed an intermediate robustness (robustness = 0.58, Table 4) because most of the genes contribute to generate a specific pattern of adhesion molecule expression after T-cell activation.
The pattern of adhesion was analysed to determine the number of cells rolling, statically adherent or transmigrated.
Therefore, we investigated the in vitro effect of DHEA on the expression pattern of adhesion molecules of human endothelial cells and neutrophils.
We have studied whether N-methylformamide can affect the expression pattern of adhesion molecules and the attachment behaviour of M14 human melanoma cells.
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