Sentence examples for patterns and ligand from inspiring English sources

Although DDT is known to cause rodent hepatic tumors, the marked species differences in PXR/CAR structure, expression patterns and ligand preference as well as significant species-specific differences in steroidogenesis, especially CYP17A1 expression and activity, confound the extrapolation of these results to humans.

Although DDT is known to cause liver tumors in both mice and rats, the marked species differences in PXR/CAR structure, expression patterns and ligand preference as well as significant species-specific differences in steroidogenesis, especially CYP17A1 expression and activity, confound the extrapolation of these results to humans.

Based on GPRC6A's expression pattern and ligand preferences, we hypothesize that the receptor may impact energy metabolism via regulating physical activity levels.

The authors employed it for analysing the relation between interaction pattern similarity and ligand or binding site similarity among thousands of complexes of diverse proteins [17].

The bis-substitution pattern and diastereoselective ligand exchange is attributed to the steric bulk of the glycoluril backbone that prevents further ligand substitution.

This study concluded a continuum character of the organogold(i) species ranging from metal stabilized singlet carbene to metal coordinated carbocation depending on the substitution pattern and the ligand on gold.

Finally, we distinguished proteins by the mutual recognition pattern of proteins and ligand clusters.

Each exhibits distinct patterns of tissue distribution and ligand specificity (Kersten et al, 2000).

One of the above methods, a post-screening analysis for visualizing protein-ligand interaction (VISCANA) which analyzes the receptor and ligand pattern of interaction on the basis of quantum theory is an approach proposed by Amari et al[ 12].

This generality was evidently useful in obviating a clear relation between the pairwise pocket dissimilarity patterns and the corresponding pairwise ligand patterns, which were generated by the exact same implementation.

These three ER subtypes have been shown in many cases to have distinctive tissue distribution patterns, dissimilar ligand affinities, and different patterns of gene regulation following ligand exposure.