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In mouse ES cells Loh et al. performed RNAi-based knockdowns for Oct4 and Nanog and compared the differential expression pattern with potential binding sites of these factors, using a ChIP-PET approach [15].
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Using computational methods, sequence patterns with potential to form G4 DNA were mapped within 32996 hotspots and corresponding flanking regions in human.
We also note that although our results show microbiome patterns with potential roles in cancer, we cannot determine causality as part of this study.
A facilitating step towards understanding the basis for gene expression variability is associating genome wide transcription patterns with potential cis modifiers of gene expression.
It is thus concluded that the SlbZIP proteins have complex and varied dimerization patterns with potential to homodimerize with themselves or members from the same subfamily as well as heterodimerize with members from other subfamily.
The present experiment is the first to show that CPA can be successfully applied to analyze Tb recordings of a passively wintering wild mammal in order to unravel its foraging patterns with potential applications to other northern carnivores.
We took the mapping information of the 17 Xq28-mapped diseases and listed those genes for each disease, whose expression pattern overlap with potential affected tissues, and which are located in or nearby the respective linkage region.
In addition, Spearman correlation analysis is also undertaken to measure the bivariate associations between landscape metrics and land suitability values to specifically address the consistency of the cancer-treating growth pattern with the potential of the study area.
The present situation shows a clear geographic pattern, with the potential for additional spread across the border between the provinces and within each of the provinces.
Analysis of the coding region to detect polymorphism patterns associated with potential key functional regions of the gene detected three regions that exhibited higher diversity than the rest of the gene at positions 250 450 bp, 900 1100 bp and 1200 1350 bp (Additional file 2: Figure S6D, Additional file 1: Table S4).
Its relationship with demographic and socio-economic factors is similar to other forms of OA but the pattern of association with potential determinants, together with the form and function of the midfoot, suggest a central role for mechanical load in this phenotype.
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