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The models in Fig. 1 depict the basic mediation pattern we tested.
Based on this localization pattern, we tested whether dystonin-deficiency leads to structural defects in cardiac muscle.
In order to test the hypothesis that a combination of Gef and TAM would result in a similar ER β localization pattern, we tested whether Gef plus TAM affects ER β localization in EGFR wild type A549 cells.
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"To develop these patterns, we tested thousands of subjects across different age groups, gender and race in all sorts of environments," Yang says.
To assess whether the hybrid misregulation also exhibited brain-specific patterns, we tested the allelic expression of several imprinted genes including H19, Peg10, Kcnq1ot1, Plagl1, and Meg3.
To proof whether 'nonreactive' hornets did not respond to shimmering or showed any odd reaction patterns, we tested the time courses of the respective behaviors of hornets categorized as 'nonreactive' for the existence of any obscure responsiveness.
To test the hypothesis that some items might present different reporting patterns, we tested for interaction terms between each item and gender.
In addition, in order to probe putative mechanistic explanations to the observed patterns, we tested whether the mito-sensitive genes exhibit biases in their representation amongst candidate genes for female-specific, male-specific, sexually-antagonistic and combined fitness.
Due to the high variability among treatments and the fact that compounds showed different emission patterns, we tested eight models with different variance structures for each compound according to [ 80].
If a clear pattern was apparent in the full model in the signs of coefficients for different months, then to simplify and detect seasonal patterns, we tested a model with season based on the coefficients against the model that included all months.
Out of the 635,712 possible patterns we tested, both methods call 635,483 insignificant, both call 49 positive, and they disagree on 180. Figure 8D plots the number of significant hits identified relative to dinucleotide scrambled sequences using shuffled (blue) and non-shuffled (red) non-ChIPed motifs.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com