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Surveyors were mapping out metes and bounds to tame the jumbled countryside with the gridiron pattern we know today.
Domestic violence murders are often preventable because they follow a predictable pattern: we know what signs of abuse look like and we know that a woman's chances of being killed by her partner increases significantly when he has access to a gun.
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When our camera showed this pattern, we knew that we had realized the atom laser.
Before this shell, the earliest geometric pattern we knew of was on a piece of ochre from Blombos Cave in South Africa, dating to around 75,000 years ago – comfortably within the time-frame of Homo sapiens.
And when we see the four main characters dancing in their symmetrical and formal patterns, we know that the societal facade merely conceals the swirling passions underneath.
"When you look at the trajectories and you look at the wind patterns, we know that more of it will be moving in," Ms. Rheams said.
Once we identify the patterns, we know what to target.
Thus, of the 15 different genes regulated by nodal-related signalling whose expression patterns we know, all are expressed in a restricted fashion (for example, see Fig. 2A,B), and of the 31 genes regulated by activin B, 28 are expressed ubiquitously (for example, see Fig. 2C F) and three in a restricted fashion.
James Poniewozik of Time did not enjoy the flashforwards, commenting that they were "the first of the flashforwards that resembled one of the bad old flashbacks, in that it just reconfirmed character traits we already knew and showed Jack and Kate falling into patterns we knew from the past … I didn't get much from it".
We intuitively understand that the way animals move at large scales determines the extent of their home range and their migratory patterns – and we know that these features are relevant to decisions about the location, size and distribution of protected areas.
"We chose not to use patterns that we know too much, we try to go back to the basics/roots.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com