Based on the Retro-MeP-EGFP expression pattern, we hypothesized that Retro-MeP-MECP2-E1 and -E2 vectors (Figure 4A) may in fact recapitulate low-level endogenous MeCP2 expression in non-neuronal cells.
Based on the known structure of dystonin isoforms and their localization pattern, we hypothesized that the absence of this protein in dt mice would lead to perturbations of the primary cytoskeletal networks, namely the microfilaments, microtubules and desmin intermediate filament systems.
Consistent with PIN localization patterns, we hypothesize that auxin transport in moss gametophores occurs in a localized manner, to remove auxin from the leaves and meristem without detectable long-distance flux [ 62].
Given the known position of vertebrate Vent genes in the gene regulatory network governing DV patterning, we hypothesized that amphioxus Vent genes might be regulated by Bmp signaling.
Based on their high sequence similarity (99% amino acid identity) and the correlation between their mRNA accumulation patterns, we hypothesized that AtRabD2b and AtRabD2c might have some functional overlap that is not shared by AtRabD1 and AtRabD2a.
Although lung tissue is more heterogenic and does not possess a prevalent cell type for driving gene expression patterns, we hypothesized that eGWAS of ARDS samples will generate biologically meaningful results.
We do not know exactly why six subjects are showing the opposite pattern, but we hypothesize that individual endocrinological differences might be involved [19].
This patient has DESH pattern and we hypothesize that some of the variability in clinical symptoms (non-monotonic decline) seen in certain AD patients [ 36] is related to CSF (and vascular) dysfunction and rather than primary AD pathology.
By analysing morphological traits that may have been positively selected by subterranean life and demography that might be associated with substitution rate and pattern changes, we hypothesized that, contrary to the findings of previous studies [ 4– 7], in this system, a molecular signature would be associated with subterranean convergence that might be identified at a whole genome scale.
Given that many elements of the transcriptomic and proteomic signatures of drought response in Populus, Solanum and Hordeum are found in differential transcript and protein patterns of Pachycladon, we hypothesize differences in drought resistance and water use efficiency between Pachcyladon species.
