In order to study the effect of an excess of small patterns we constructed a negatively skewed distribution (Fig. 8a) by cutting away all patterns above the line of symmetry ( ϕ max ) and adding smaller patterns instead.
To explore epidemiological scenarios capable of explaining these patterns, we constructed compartmental models that focused on how A. phagocytophilum exposure and infection dynamics affected pathogen prevalence in roe deer.
Based on the clustering patterns, we constructed seven real-time quantitative PCR amplicons covering approximately 90% of the described microbiota diversity.
To identify each of these patterns we constructed multiple contrasts, and a voxel cluster was only identified if it simultaneously satisfied all of the contrasts (p<.05, uncorrected; minimum cluster size = 8 voxels).
Using the different overrepresented binding patterns, we constructed an interacting transcriptional network.
To explore broad patterns, we constructed a general linear model of expression level, in which we fitted feather and morph as predictor variables together with their interaction.
To unveil their detailed venoms and their evolutionary patterns, we constructed venom gland cDNA libraries and genomic bacterial artificial chromosome (BAC) libraries for Bungarus multicinctus and Naja atra, respectively.
To obtain a catalog of genes involved in larval mimetic and cryptic pattern formation, we constructed expressed sequence tag (EST) libraries of larval epidermis for P. xuthus, and P. polytes that contained 20,736 and 5,376 clones, respectively, representing one of the largest collections available in butterflies.
To comprehensively search the genes involved in larval body pattern formation, we constructed cDNA libraries derived from the whole epidermis during the third and the fourth molting periods, and sequenced 20,736 clones of P. xuthus and 5,376 clones of P. polytes (Table 1).
Using 1,093 and 824 genes from the down- and up-regulated patterns, respectively, we constructed a network of genes composed of 11 modules (from 0 to 10), shown in Fig. 7a.
