Sentence examples for pattern recognizing receptors from inspiring English sources
The epithelium forms a physical barrier at the apical layer preventing microorganisms from entering the cellular layers that express pathogen pattern recognizing receptors such as TLR5 [28].
Toll-like receptors (TLRs) are pattern recognizing receptors (PRRs) and play an important role in regulating human's immune system.
Thus, TLR5 is the major pathogen pattern recognizing receptor of HCECs to initiate the inflammatory response toward P. aeruginosa.
NOD2 was shown to act as an intracellular pattern recognizing receptor for ssRNA viruses.
The current version of database contains around 500 patterns recognizing receptors from 77 distinct organisms ranging from insects to human.
During RNA virus infection, double-stranded RNAs (dsRNA) and uncapped transcripts generated during replication can serve as pathogen-associated molecular patterns recognized by innate immune receptors [1], [2].
In particular, Toll-like receptors (TLRs), a family of pattern recognition receptors recognizing conserved commensal bacterial products (including lipopolysaccharide, DNA, and lipoteichoic acid), mediate protection from epithelial injury and play a crucial role in the maintenance of intestinal epithelial homeostasis in normal steady state conditions [ 4].
Cells in innate immune system can recognize pattern recognition receptors (PRRs) and pathogen-associated molecular patterns (PAMPs).
On and in sentinel cells, a variety of germ line encoded pattern recognition receptors recognize and bind potentially harmful substances, which activates signaling pathways and releases proinflammatory cytokines mainly including IL-6 and tumor necrosis factor-α (34).
Because pattern recognition receptors recognize a number of oncogenic infectious agents and launch an immune response against them, inherited variation in their structure may modulate cancer risk and, possibly, influence cancer progression.
IFIH1, encoding melanoma differentiation-associated protein 5 (MDA5), is a member of the RIG-I-like receptor family and functions as a cytoplasmic pattern recognition receptor recognizing viral double stranded RNA (dsRNA).
