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Surfactant proteins (SP -A and -D are pattern recognition moleculeSP -Athe collectin fandly of C-type lectins.
C1q and members of the defense collagen family are pattern recognition molecules that bind to pathogens and apoptotic cells and trigger a rapid enhancement of phagocytic activity.
Toll-like receptors (TLRs) are critical pattern recognition molecules of the innate immune system.
Their pattern recognition molecules allow them to readily recognize and rapidly respond to bacteria that breach the epithelium [7].
Pattern recognition molecules could be an important player in the initiation of an exaggerated inflammatory response leading to intestinal injury in NEC.
While TepI and TepII are expressed constitutively at low levels, and only upregulated upon immune challenge [61], we found that spaceflight affects the constitutive expression of all these classes of pattern recognition molecules.
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The long pentraxin PTX3 is a soluble Pattern Recognition Molecule (sPRM) with non-redundant roles in resistance to selected pathogens, such as the opportunistic fungus Aspergillus fumigatus.
The present study was designed to investigate the role in UTI of the soluble pattern recognition molecule pentraxin 3 (PTX3), a key component of the innate immune system.
While further research is needed to define its function, our data indicate that MgC1q is a pattern recognition molecule able to recognize pathogens during innate immune responses in Myitilus galloprovincialis.
As a versatile charge pattern recognition molecule, C1q is capable of engaging a broad range of ligands via its heterotrimeric globular domain (gC1q) which is composed of the C-terminal regions of its A (ghA), B (ghB) and C (ghC) chains.
SPD, a 43-kDa member of the collectin superfamily, is a part of lung surfactant and has been shown to have an important role in the innate immune system by working as a pattern recognition molecule [7].
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