The number of putative microRNA targets (19 of 177 genes) in the temporal down-pattern was significantly lower than the number of targets (155 of 463 genes) in the temporal up-pattern (p value < 0.001).
This association was even stronger for postmenopausal women, also showing a marked dose-response pattern (P-value for trend < 0.001).
When using the flavonoid genes CHS, DFR, F3H and LDOX, 208 genes (regulon 2) showed a matching expression pattern (P-value 0.01).
172 out of the 519 genes down-regulated in ams were expressed significantly higher in the wild type anther than the inflorescence, while 102 of the 849 up-regulated genes showed this pattern (P-value < 0.05, Figure 1D, Additional file 2), suggesting that preferential anther expression contributed to the difference between the two studies.
In this part we propose to derive asymptotic developments for pattern p-values from their recursive expressions.
A Students T-test was used to compare OMS values of the complete datasets (N = 75) to determine statistical significance: this confirmed that enaGC1 mildly enhanced cindrRNAi mis-patterning (p-value = 0.02438, significant at the 5% level).
Additionally, the expression level of Rafflesia VGTs is positively correlated with similarity to Vitis-like coding patterns (p-value = 1.4×10−7), suggesting that the convergent host-like coding patterns we identify in some Rafflesia VGTs are biologically meaningful.
This indicates that microRNA is especially concentrated in the regulation of temporal up-pattern genes (p value < 0.001).
Fourthly, the FV pattern had P values less than 0.05 but higher than 0.01 in certain subjects.
Table 3 shows the frequency of domain genes in each structural pattern and the P value by the Fisher's exact test (detailed information is provided in Supplementary Tables S2 [see Additional file 7] and S3 [see Additional file 8]).
An even stronger effect was observed among individuals not treated with antiviral therapy (weeks 1 4: IR, 2.14; 95% CI, 1.62 2.84), with a similar pattern of resolution (P value for interaction =.03) (Table 4).
