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Proliferation and migration responses of mesenchymal stem cells seeded at pattern origins were observed with time-lapse video microscopy and analyzed using both manual and automated computer vision-based cell tracking techniques.
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The ultrastructure, surface pattern, origin of different smooth pads, and their evolution are described.
Hydrochemical facies interpretation is a useful tool for determining the flow pattern, origin of chemical histories of groundwater.
However, an appreciation of the amount, pattern, origin, and persistence of population-level genetic variation within an infant's GIT is crucial for understanding the evolutionary forces at work during the process of colonization.
Comparative phylogenies between biparental (nuclear) and uniparental (chloroplast and mitochondrial) markers are useful for resolving phylogeographic patterns, origin of hybridization, and assessing the migratory routes of species [ 40- 42].
At the most fundamental level, our knowledge about the distribution pattern of origins in each of the chromosomes, among different cell types, and whether the physiological state of the cells alters this distribution is at present very limited.
However, some non-specific binding was still observed, which had punctuate or small circular pattern the origins of which is, presumably, the intimal layer of larger vessels and intestinal content (blue rectangle Fig. 4C, magnified in 4F).
Nevertheless, lower pol-prim levels or weakened origin association that approaches below a minimal threshold may alter the temporal and spatial pattern of origin firing in S phase, as was shown for the key origin firing factors Cdc45 and Sld3 (Mantiero et al., 2011; Tanaka et al., 2011).
Therefore it is likely that while origin spacing appears to be short when averaged across the population, this most likely reflects a stochastic pattern of origin activation at larger intervals in individual cells rather than unique pattern shared in all cells.
This technology has been applied to myriad genomes, including the human genome, providing insights into evolutionary relationships, migration patterns, familial origins, biomedical risks, and forensic connections.
By using these modulation patterns, the origins of the three anisotropies have been determined.
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