Sentence examples for pattern of substitution from inspiring English sources

Structure activity relationship (SAR) studies suggest that the pattern of substitution in the phenyl ring is closely related to the biological activity of this class of compounds.

Such differences in sampling procedure may also explain the neutral pattern of substitution across DIII observed among the Venezuelan Pvama1 sequences, in contrast to DIII from other regions.

However, the detection of sites with high dN/dS values may be an artifact of the pattern of substitution strongly affected by contrasting evolutionary constraints acting on both ORFs within the overlap region.

Therefore, the pattern of substitution across the phylogeny of mammals coding region does not explain the lack of common variation in humans nor the lower divergence along the human-chimpanzee lineages for the second part of the gene.

In this work we decompose Q into three factors: (i) the rate of substitution; (ii) the neutral pattern of substitution; and (iii) the site-specific pattern of substitution.

The physicochemical properties and therapeutic applications of natural coumarins depend upon the pattern of substitution.

The pattern of substitutions is suggestive that BMP3 gene probably evolved in a non-neutral manner, possibly driven by positive natural selection, in modern human populations.

The pattern of substitutions and functional consequences predicted by three bioinformatic programs was significantly different among concurrent CVs, and CVs occurring solely in HGMD or in dbSNP.

To identify the cause for this, DRB1 sequences, a representative case of a typical nonlinear pattern of substitutions, were examined.

The total number of DIMs sampled was so large (≈344,000) that we believe they can provide a general pattern of substitutions in segmental duplications.

The presence of a third paralog might also affect the pattern of substitutions between other duplicated genes, but this is a problem for most studies on duplicated genes.