Sentence examples for pattern of reversion from inspiring English sources

Similarly, a stepwise pattern of reversion of resistance associated mutations (RAMs) to wild-type was described in one multi-drug resistant HIV-positive individual by comparative analyses of longitudinal population-based sequences [10].

The combined data demonstrated that S. sonnei was significantly more likely to be resistant to trimethoprim- sulfamethoxazole and ceftriaxone, despite ceftriaxone resistance not becoming evident till period C. The overall pattern of reversion of sensitivity to ampicillin and chloramphenicol was mainly observed with respect to S. sonnei isolates.

However, the extent of reported genotypic changes during STI differs between studies, and only a few of these studies described the patterns of reversion of mutations to wild-type codons, which occur as a combination of re-emergence of preexisting variants with fewer resistance mutations and actual reversion of codons within a viral genome.

DOI: http://dx.doi.org/10.7554/eLife.11282.020 10.7554/eLiFigure82.021 Figure 6 figure supplement 1. Patterns of reversion at the amino acid level are similar to those at the nucleotide level.

To quantify patterns of reversion and fitness cost, we classified sites in the approximate founder sequence of the viral populations in each subject as being identical or different from the HIV-1 group M consensus.

Overall, we find that divergence along the genome, correlation with cross-sectional diversity, and patterns of reversions all show similar dynamics at the amino acid and nucleotide levels.

The present study aims to characterize the evolutionary patterns of the reversion of resistance mutations during treatment interruption.

The research design is based on the daily-and-hourly specific mean reversion pattern of highway traffic, which can be used to define a recurrent congestion benchmark.

The proliferation-associated molecular signal pathway with a high level of TERT activity occurring in the de-ATSC and the pattern of gene expression revealed a reversion toward a more immature phenotype of the cells.

Again, this pattern of results may be indicative of mean reversion.

Using a survival analysis model, Trignetti et al. did not find a pattern in the reversion of RT mutations during treatment interruption [21].