Sentence examples for pattern of rearrangement from inspiring English sources

Exact(6)

The pattern of rearrangement provides considerable insight into the mechanisms involved in rearrangement of genes in this genome.

This pattern of rearrangement suggests a unique mechanism of tumorigenesis within prostate cancer that may be associated with the known influences of androgen receptors and other regulators of gene expression.

Although the role of homologous recombination in genomic rearrangements across the replication axis has not been elucidated, Tillier and Collins proposed an alternative model for the observed pattern of rearrangement [ 74].

The pattern of rearrangement indicates that the mechanism of rearrangement involved a tandem duplication of the entire mitochondrial genome, followed by random and nonrandom loss of one copy of each gene.

There can therefore also be any number of additional tumour suppressor genes in between these two which would give the same pattern of rearrangement, and our data suggests that there may be at least one further candidate gene located in 8p22.

In this study, we applied interphase FISH on a subset of post-Chernobyl tumour that became clinically apparent within a short period of time after exposure to radiation (4 8 years) and compared the data generated with that from a group of papillary cancers with a longer latency (9 12 years), in order to study the pattern of rearrangement of the RET oncogene within these two groups.

Similar(54)

However, the pattern of rearrangements in derivative chromosomes is complex.

In cases of disagreement on the pattern of rearrangements, three independent observers with extensive cytogenetic expertise manually checked and decided the rearrangement pattern.

After a second nested PCR, the products were sequenced directly from both ends, which revealed that a complex pattern of rearrangements had occurred to produce the lavender allele.

They ignore the fact that, even though their PGD model can explain the observed data using fewer rearrangement steps than the WGD model, the PGD model requires an exceedingly unrealistic pattern of rearrangements to happen.

The pattern of rearrangements seen on 8p may be a consequence of the high density of potential targets on this chromosome arm, and ARHGEF10 may be a new candidate tumour suppressor gene.

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