Sentence examples for pattern of origin from inspiring English sources

Nevertheless, lower pol-prim levels or weakened origin association that approaches below a minimal threshold may alter the temporal and spatial pattern of origin firing in S phase, as was shown for the key origin firing factors Cdc45 and Sld3 (Mantiero et al., 2011; Tanaka et al., 2011).

To examine the relationship of replication initiation with transcription, we initially compared the location of known transcription start sites (TSS) contained in our array to the pattern of origin peaks obtained in MCF-7.

Therefore it is likely that while origin spacing appears to be short when averaged across the population, this most likely reflects a stochastic pattern of origin activation at larger intervals in individual cells rather than unique pattern shared in all cells.

Heichinger et al. [4] calculated a minimum length of S-phase of 19 min. Eshaghi et al. [5] found that the duration of S phase after HU release was ∼60 min. It has been shown that in S. cerevisiae the pattern of origin activation is not affected by continuous exposure to HU, although HU causes an expansion of S phase time frame [27].

Members in each clade show monophyletic pattern of origin.

The two strains showed a comparable pattern of origin firing by genome-wide analysis of BrdU incorporation and by two-dimensional gel electrophoresis (2D gel) analysis, suggesting that origin firing does not depend on Sen1.

At the most fundamental level, our knowledge about the distribution pattern of origins in each of the chromosomes, among different cell types, and whether the physiological state of the cells alters this distribution is at present very limited.

The overall development as well as the regional patterns of origin differs significantly across the four main material categories.

This was done by determining the phylogenetic position of each of the predicted proteins in this genome followed by their clustering into major distinct phylogenetic patterns of origin (i.e., cyanobacterial, common to cyanobacteria and other bacteria, bacterial origin but not shared with cyanobacteria except ACBU02, archaeal, and viral).

The emergence time points of the major and minor categories of molecular functions in the timeline of FFs revealed remarkable patterns of origin in the five evolutionary phases.

This approach has been proven effective in inferring the prehistoric migrations of modern humans into Europe.8, 9 Our previous study on Hg O3-M122 indicated a clear pattern of southern origin of this lineage and provided a solid evidence for the proposed southern route.10 Through detailed analysis of Hg N-M231, Rootsi et al.5 also detected the same migration route via Southeast Asia.