Sentence examples for pattern of malformations from inspiring English sources

To report a case of embryopathy due to misadministration of methotrexate in the setting of suspected ectopic pregnancy that resulted in a different pattern of malformations than is typically seen with methotrexate.

Although the association between prenatal exposure to old generation antiepileptic drugs (AEDs) and major congenital malformations has been studied for many years, it is not clear whether any specific AED, or AED combination, is more harmful than others, or whether any pattern of malformations can be considered specific for any given drug.

There was no specific pattern of malformations.

No specific pattern of malformations was identified.

No specific pattern of malformations was revealed.

There was no specific pattern of malformations in our study.

Eight case reports documenting a unique pattern of malformation in infants prenatally exposed to cyclophosphamide have been published [ 85].

Importantly, among the exposed group, all seven major malformations occurred among the 96 women receiving polytherapy; however, no specific pattern of malformation was found.

As discussed by Landrigan (4), the pattern of malformation noted has suggested that the critical window of exposure is in the first trimester.

The most common pattern of malformation observed in infants with methotrexate-induced embryopathy includes growth deficiency, craniosynostosis, micrognathia and skeletal abnormalities, which are similar to those in individuals with Miller syndrome [ 21, 22].

Although no epidemiological studies of prenatal exposure to cyclophosphamide have been published, the similar pattern of malformation seen in case reports suggests that cyclophosphamide is a human teratogen, although the magnitude of risk is unknown.