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Exact(8)
RLC_ egBianca_1 and RLC_ egAngela_2 copies have a similar pattern of insertion time where most of the copies were inserted into the genome 0.5 – 4.5 Mya.
In contrast, CACTA elements did not show this pattern of insertion preference.
This pattern of insertion and deletion was also characterized by population and family studies [ 46- 49].
Mycobacterial isolates from 77 patients, initially diagnosed with M. intracellulare lung disease were re-analyzed by multi-locus sequencing and pattern of insertion sequences.
The pattern of insertion suggests that promoter regions of protein-coding genes are preferentially targeted, while the 3′ ends and introns are affected to a lesser extent.
The oldest of the subtypes, A, show a clear difference in the pattern of insertion in the genome to the rest of this family of retrotransposons, however the mechanism behind this is unclear.
Similar(52)
One of the CC176 strains, namely Hungary 19A, has a pattern of insertions different from the other CC176 strains, but very similar to the CC146 strains, suggesting for this strain a genealogy that violates the MLST schema, or a recent acquisition of the entire locus from a CC146 strain.
We also compared the distribution pattern of insertions depending on donor site.
A complex pattern of insertions and deletions was identified in this region that is rich in proline (P), glutamine (Q), aspartic acid (D) and glutamic acid (E).
The evidence for a relaxed purifying selection in Drosophila tra is corroborated by the pattern of insertions and deletions (indels) for tra that is not taken into account by PAML's analysis of coding sequences.
Specific patterns of insertion suggested read-through transcription, enhancer effects, and disruption of tumor suppressors as likely mechanisms for genotoxicity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com