Sentence examples for pattern of inactivation from inspiring English sources
A puzzling pattern was observed in pl.03, where two loci showed completely skewed pattern of inactivation, while two other loci presented random inactivation (Figure 1).
This chimerical enzyme was the first in which we observed a pattern of inactivation by MMTS that resembled that of TbTIM.
In hESCs, methylation specific analysis of a polymorphic tri-nucleotide repeat at the HUMARA gene show three out of four hESC lines possess skewed XCI while one has a random pattern of inactivation [33].
Only one of the 20 asbestos-induced MMs showed loss of p53 expression (Fig. 3B), and that single sample retained expression of Arf, consistent with our previous work showing a reciprocal pattern of inactivation of Tp53 in asbestos-induced MMs from Nf2 mice that had retained expression of Arf [5], [6].
Typically, in the female patient, the cardiac and the muscle involvement showed a patchy distribution because of the pattern of inactivation of the X chromosome [4].
Furthermore, a pattern of inactivation similar to EPHB2 has been observed for EPHB4 and EPHB3 in colorectal tumors and/or cell lines, respectively [ 5].
The similarities in the patterns of inactivation between the two t(X A) involving chr21 (GM01730 and GM08134) strongly support the role of DNA sequence in determining inactivation status.
While many X-linked genes undergo X-inactivation, some degree of expression heterogeneity among females has been reported: 15% of X-linked genes escape inactivation and 10% of X-linked genes exhibit variable patterns of inactivation, which might help explain the widespread gender disparity in disease risk and pathogenesis [ 3].
We tested the pattern of X inactivation in blood DNA from our subjects to see if nonrandom X inactivation might play a role in the neurocognitive phenotype.
As the cloned embryos matured, a pattern of X inactivation emerged similar to that in normal development.
Several studies have been conducted with human and mouse XXY and XXX triploid embryos and embryo-derived cell lines, to try to determine the pattern of X inactivation.
